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Peptides effective for inhibiting cholesterol aggregation in the vascular wall

A work demonstrates that peptides derived from a LRP1 receptor sequence are very effective inhibiting the aggregation of LDL (low density lipoprotein, also called 'bad' cholesterol) that takes place in the vascular wall during development of atherosclerosis.

Only the introduction is translated


A metabolite from a drug against diabetes, a possible treatment for neurodegenerative diseases

MIN-102, a metabolite from a drug against diabetes, could be useful for treating some neurodegenerative diseases, as scientists think. To confirm this hypothesis, a project has been launched with the involvement of the CSIC’s Instituto de Investigaciones Biomédicas de Barcelona, the Hospital Universitari 'Sant Joan de Déu' and the University of Lleida. The research project is led by the company Mynorix Therapeutics.


Obtained a synthetic single molecule which inhibits the anticoagulant heparin

Scientists at the IQAC-CSIC have obtained a synthetic single molecule which inhibits heparin, the most used anticoagulant drug nowadays. The development has been possible by dynamic combinatorial chemistry. Dynamic chemistry makes possible quickly discovering active molecules and drugs.


Fagomine, effective in long term prevention of type 2 diabetes risk factors

Researchers from the Institute of Advanced Chemistry of Catalonia CSIC study the beneficial effects of natural compounds in food. According to the conclusions of a recent study, fagomine, a natural molecule, counteracts the effects of a high-fat diet.


Scientists study the role of a protein in the non-alcoholic fatty liver disease

Scientists at the Institut d'Investigacions Biomèdiques (CSIC-IDIBAPS) and at the Institut de Química Avançada de Catalunya, of the CSIC, have been awarded one of the 6 grants of the BBVA Foundation for biomedical research. The scientists will study the implication of a protein in  Nonalcoholic fatty liver disease, which is involved in obesity related diseases.